Thursday, March 1, 2012

Hamster Health Issues / Diseases (Part IX)



Hamster Health Issues / Diseases



═════════════════════
·                     Hamsters' specific issues and diseases
·                     Common Health Issues and Red Flags
·                     Disease Susceptibility
·                     Recognition of Hamster Diseases
·                     Hamster Conditions
1.                  Teeth Problems
2.                  Toothless Hamsters
3.                  Trauma
4.                  Respiratory infection
5.                  Head tilt (wry neck, torticollis)
6.                  Hypothermia
7.                  Fight wounds
8.                  Bladder Stones
9.                  Cancer
10.              Abscesses
11.              UPDATE: Wet Tail (Proliferative Ileitis)
1.                   
1.                  Hamster-safe Wet Tail Management 
12.              Salmonellosis
13.              Rabies
14.              Lymphocytic Choriomeningitis
15.              Demodectic Mange
16.              Intestinal Parasites
17.              The pinworm and the tape test
·                     *Hibernating
·                     Hamster resuscitation
·                      
·                     SPECIAL: Hamster Medications
o                  Antimicrobials
o                  Antiparasitics
o                  Miscellaneous drugs for various conditions
o                  Routes of Administration

═════════════════════
Health Problems (3)

















  • Hamsters' specific issues and diseases with some images available (10) 






















  • Common Health Issues and Red Flags to watch our for (9)










  • Disease Susceptibility

  • Hamsters tend to be affected by relatively few naturally occurring diseases. Their susceptibility, however, to a host of infectious diseases of other animals, including people, and the case with which these diseases can be transmitted to hamsters have made them very popular laboratory animals for biomedical research. ‘Teddy bear’ hamsters and other genetic varieties tend to be much more susceptible to disease and sensitive to antibiotics and other drugs than golden hamsters. (1)








  • Recognition of Hamster Diseases

  • Because hamsters are very small, nocturnal (night- active) and not closely observed, the early signs of illness are frequently overlooked or not noted at all. Hamster owners must be constantly vigilant for signs of illness and must seek immediate veterinary assistance when illness is suspected. (1)

    Sick hamsters often become irritable and frequently bite. They are usually reluctant to move about and walk stiffly when forced to do so. Their eyes often look dull and sunken, and frequently have a discharge. Sick hamsters often stop eating or greatly reduce their intake of food. Consequently, weight loss is a common sign (not necessarily an easy one to recognize) of illness in hamsters. Fluid losses from diarrhea also may cause marked weight loss. Sudden intestinal disease (with accompanying diarrhea) is the most common illness of hamsters, especially amongst those being weaned or recently weaned. If the serious accompanying dehydration is not recognized immediately and corrected with appropriate fluid therapy at the direction of a veterinarian, death is probable. (1)

    Predisposing factors of bacterial diseases (11) 










  • Hamster Conditions








  • Teeth Problems

  • The incisor (front, gnawing) teeth grow continuously for the life of the hamster (this is true for all rodents). They receive continuous wear as the uppers and lowers contact each other,
    preventing overgrowth. Misalignment of either the upper or lower incisors because of previous injury, abscess formation or malnutrition may result in overgrowth of one or more of the teeth.(1)

    Overgrown incisor teeth usually cause serious injury to the roof of the mouth. Sometimes the lower incisors actually grow through the roof of the mouth and into the nasal cavity! Initial signs of this problem are inappetence and drooling Total lack of eating, weight loss, and a foul odor from the mouth may be noted later. These signs often are completely overlooked.(1)
    A veterinarian must carefully trim the overgrown incisors and extract them from the roof of the mouth. Antibiotics are prescribed because of the high probability of infection following this type of injury. Periodic trimming of the incisors is usually necessary for the remainder of the hamster's life.(1)
    Some popular hamster houses made of plastic had holes in the horizontal and vertical tubes originating from the main rectangular enclosure. Hamsters frequently caught and broke their incisors in these holes in the plastic. The manufacturer has since made the holes smaller, and this injury is seen less frequently now. (1)








  • One more potential problem: Toothless Hamsters (10) 










  • Trauma

  • Hamsters are easily injured. They are frequently dropped while being handled (especially by children), or after they bite. Pet hamsters allowed ‘free run of the house’ (even for very short periods) are often stepped on or kicked and seriously injured or killed. Hamsters are frequently injured while inside an "exercise ball". This is a clear plastic
    sphere that is propelled along the floor by the action of the hamster running inside it. Injuries occur when a person accidentally kicks the ball or when it falls down a flight of stairs. Hamsters often perish when they are forgotten and left in these devices without food and water. In spite of the clever design and obvious benefits of this device, hamster owners must continually supervise its use. Parents must be made aware by their children that it is in use.
    Trauma may result in broken bones and/or serious internal injuries or death. A fall of over just a foot or more may result in a broken back, for which there is no practical treatment. (1)

    Injured hamsters should be immediately examined by a veterinarian. Broken bones are very difficult to manage. Often an appliance (splint, etc.) to immobilize the broken bone will not be applied because of the sometimes greater problems they impose on the broken limb. The veterinarian will determine the best course of action in each situation. (1)








  • Respiratory infection

  • Signs include sneezing, wheezing, lethargy, nasal or eye discharge, or difficulty breathing. Various bacteria may cause these infections. Treatment involves using antibiotics with caution, since hamsters may develop severe bowel upsets during treatment. To minimize the risk of respiratory disease, provide a warm, clean cage; avoid the use of wood-chip beddings; and feed your hamster a balanced diet. (5)








  • Head tilt (wry neck, torticollis)

  • This condition is usually due to internal ear infection, sometimes secondary to a respiratory infection. The hamster often tilts her head to one side and loses her balance, falling or circling when she tries to walk. Bacteria are the usual cause and treatment is with antibiotics.(5)








  • Hypothermia

  • Golden hamsters are very sensitive to cold and may become unconscious at temperatures in the mid-60s or lower. Their breathing is very shallow and they often appear dead, but may slowly revive when warmed in one’s hand. Avoid air temperatures below 70 degrees in the room where your hamster lives, and keep the cage away from cool areas, such as windows. Provide warm bedding, such as recycled paper or tissue paper, for your pet to nest in; a small nest box also helps conserve body heat when the hamster is sleeping. (5)








  • Fight wounds

  • Hamsters tend to be aggressive and antisocial with each other; they often fight if housed together. This may result in bite wounds; their eyes are also easily popped out of the sockets during fighting. Any visible wounds on a hamster require immediate medical treatment; the risk of infection is great, and treatment of abscesses in hamsters is difficult. Early antibiotic therapy to prevent infection is the safer option.(5)









  • Bladder Stones

  • Hamsters are susceptible to formation of stones within the urinary tract. The bladder is the only location within the urinary tract in which a veterinarian would likely detect stones upon physical examination. (1)
    Signs of bladder stones may or may not be detected by hamster owners and are usually associated with infection within the urinary tract, frequent urination, straining on urination, blood in the urine, increased water consumption, listlessness and inappetence. (1)

    A veterinarian may be able to remove the stones. This is accompanied by appropriate antibiotic therapy. Dietary management to help dissolve the urinary stones and prevent their recurrence is not practical with hamsters. (1)








  • Cancer

  • Cancer is very common in pet hamsters. The incidence increases with age (as is the case with most animals) and is higher among females than males because of the variety of cancers that involve the female reproductive tract. Tumors of hamsters may be benign or malignant.(1)

    Hamsters are vulnerable to an unusually large number and variety of benign cancers. Cancers involving hormone-producing organs (such as the thyroid and adrenal glands) are among the most common tumors found in hamsters. These cancers cause hormone imbalances, hair loss and changes in behavior, as well as other significant signs. (1)

    Veterinarians can often perform surgery to completely remove small external tumors. Internal tumors, however, are much more difficult to diagnose and remove. The small size of the patient, the even smaller size of the organ(s) involved, the sometimes inaccessibility of the tumor and the expense involved are some of the reasons why an owner of a pet hamster might elect euthanasia (putting the pet to sleep) or do nothing and allowing the hamster to live out its life instead of surgery in these situations. (1)

    Hamster back image (3)










  • Abscesses

  • Abscesses are most often caused by bite wounds from fighting. These wounds become infected, forming abscesses that appear as firm, painful lumps under the skin. Abscesses from injuries other than bite wounds may be indistinguishable from those that result from fighting. (1)

    Abscesses of one or both cheek pouches are also very common among pet hamsters. These commonly result from penetrating wounds to the lining of the pouch caused by harsh foods or bedding materials. It may be very difficult for you to know whether a swelling in the area of the cheek pouch is an abscess or simply food or bedding being temporarily stored within the pouch. Generally speaking, the swelling resulting from a cheek pouch abscess persists, but a pouch swelling from stored food or bedding disappears when the animal empties its cheek pouch.(1)

    If an abscess is detected or suspected, the abscess must be opened and the pus drained or removed by a veterinarian. An appropriate antibiotic also will be prescribed. Furthermore, the underlying cause(s) for the abscess must be eliminated, if possible. (1)








  • Wet Tail (Proliferative Ileitis)

  • The most serious intestinal disease of hamsters is ‘wet tail’. The bacterium suspected of causing this disease is called Campylobacter, which can also cause intestinal disease in swine, dogs, ferrets, primates and other animals. This disease most often afflicts hamsters of weaning age (3-6 weeks old), but hamsters of all ages are susceptible. Since weaning hamsters and those slightly older are commonly sold in pet stores, wet tall is a fairly common disease among recently acquired hamsters. Longhaired ‘teddy bear’ hamsters are highly susceptible to wet tall. Signs include lethargy, inappetence, unkempt hair coat, sunken, dull eyes, increased irritability, hunched posture, very fluidy diarrhea, and a wet, soiled anal area and tail. Blood from the rectum and protrusion of the rectal lining
    (prolapse) may be noted in particularly serious cases. (1)

    Hamsters with wet tail must be immediately examined and evaluated by a veterinarian. Fluid replacement, oral anti-diarrheal medication, and antibiotics will be given, along with supportive care to keep the patient warm, clean, comfortable and well nourished. Treatment is often unrewarding, and death may occur as soon as 48 hours after the onset of initial signs. This disease is not transmissible to people. (1)



  • Hamster-safe Wet Tail Management
  • (from HH's MissPixy) (22)

    1) Give your syrian hamster a few days alone without handling when you first bring her home;

    2) If you notice signs of profuse diarrhea, contact immediately a hamster-experienced vet so you can
    start on a more appropriate antibiotic;

    3) Get your hamster's water bottle filled with 50percent children's unflavored pedialyte, and 50percent bottled spring water. The dehydration that occurs from diarrhea can also kill a hamster quickly.

    4) Remove all food from your hamster at this time except for organic yogurt (My note: Always check the label!) which she can eat freely. Do not introduce any other food until stools are normal again. 









  • Salmonellosis
  • Several species of the bacterium, Salmonella, can cause serious intestinal disease (salmonellosis) in hamsters under certain circumstances. Salmonellosis is transmissible to and equally serious in people. The bacterium is usually acquired by eating food contaminated with the organism. Pet hamsters established in homes would most likely become infected via this route. For this reason, fresh fruits and vegetables must be thoroughly washed before they are offered to hamsters. Newly purchased pet hamsters may harbor the Salmonella organism, having acquired it from the colony into which they were born. (1)

    Salmonellosis in hamsters may manifest itself as sudden illness that often is fatal or as a more long-standing disease that causes weight loss. Salmonellosis can be diagnosed on stool culture by a veterinarian. Antibiotic treatment of the disease may or may not be recommended by the veterinarian, depending upon the public health implications. Euthanasia (putting the patient to sleep) would be recommended if treatment were not undertaken.(1)







  • Rabies
  • The subject of rabies inevitably comes up whenever a hamster bites an individual and
    because hamster bites are so common. Hamsters are not natural hosts of this virus. Therefore,
    the only way that a hamster could become infected with the rabies virus is to become exposed to
    infected saliva from a natural host of the virus (skunk, fox, bat, etc). This is highly unlikely,
    since hamsters are almost exclusively indoor pets. (1)








  • Lymphocytic Choriomeningitis

  • This viral disease can be transmitted from hamsters to people. A large number of cases
    in 1974 and 1975 were traced to a common infected hamster colony. Signs of this disease in
    people include recurrent fever, headache, fatigue, muscle aches, sore throat, rash and arthritis.
    The natural host in the wild for the causative virus is the rodent population. Hamsters
    would most likely acquire their infection from this source. Because hamsters are almost
    exclusively indoor pets, they are unlikely to become infected with the virus. Hamster owners
    must, however, restrict contact between their pets and orphaned wild rodents that have been
    adopted. (1)








  • Demodectic Mange

  • Mites that reside within the hair follicles and certain glands of the skin cause Demodectic mange, a common external parasite problem of hamsters. The mites cause dry, scaly skin and significant hair loss, especially over the back. (1)

    This disease is rarely a problem by itself and is frequently associated with long-standing, debilitating diseases, such as those involving the kidneys. A veterinarian should examine hamsters exhibiting hair loss as soon as possible. The doctor will do a skin scraping and examine it under the microscope. The presence of mites in the scraping confirms the diagnosis. This disease can be treated, but the patient may have an underlying problem for which there is no practical treatment or cure. (1)








  • Intestinal Parasites

  • Hamsters frequently harbor tapeworms within their small intestines. Heavy infections may cause weight loss. Lighter infections usually go undetected unless pieces of the worms pass out of the hamster's anus or appear in the faeces. People can become infected with the same organism. Tapeworms can be transmitted to uninfected hamsters (or people) when faeces harboring tapeworm eggs are inadvertently eaten.(1)







  • The pinworm and the tape test (10) 



  • This underscores the importance of restricting access to hamsters and their enclosures by very young children. All such encounters should be carefully monitored. Hamster owners suspicious of this parasite problem should submit a faecal sample to a veterinarian for analysis. The presence of tapeworm eggs in the sample (noted microscopically)
    confirms the diagnosis. The veterinarian can institute treatment. Pinworms are a less common intestinal parasitism of hamsters. These extremely tiny worms reside within the large intestines and usually cause no signs at all.
    A veterinarian via microscopic examination of the faeces can diagnose pinworm infections. Pinworm eggs passing from the anus of the hamster sometimes cause intense itching in this area. A veterinarian may be able to detect the presence of pinworm eggs by pressing tape to this area and examining it under the microscope. Pinworms of hamsters do not cause disease in people. (1)







  • *Hibernating

  • In the winter, hamsters stay in their burrows, blocking up the entrances with soil. They are not true hibernators but sleep in a grass-lined nest, waking up every five to seven days to feed from the food they stored during the autumn. (7)

    Hibernation is a physiologic adaptation of many hamster species to harsh winter environments. Hamsters are permissive hibernators who may avoid hibernation if there are insufficient food stores in the burrow or may arouse from hibernation if the temperature temporarily rises. Cold exposure is considered an important factor in inducing hibernation.(14)

    Hamsters may hibernate if the temperature falls below 8_C (48_F). Testicular regression or atrophy due to decreasing photoperiod or daylight predisposes male hamsters to hibernate. During hibernation, body temperature, heart rate, and respiration are lowered; however, the hamster remains sensitive to tactile and thermal stimulation. (14)


    While hibernating, the pulse rate of the golden hamster drops from 400 per minute to 4, and it takes a breath only twice a minute.(7)







  • If death is anticipated, resuscitation may be done (13)




  • SPECIAL: HAMSTER MEDICATIONS (31)
  • (from VSPN (Veterinary Support Personnel Network) thru Veterinary Information Network)

    WARNING: VETERINARY CONSULTATION IS STILL THE BEST WAY TO MANAGE HAMSTER HEALTH ISSUES AND CONDITIONS. THIS BLOG SUGGESTS HAMSTER OWNERS TO SEEK PROFESSIONAL ADVICE BEFORE USING ANY MEDICATION.  IT IS YOUR OWN DISCRETION IF YOU'LL ADMINISTER THE DRUGS LISTED HERE AND THIS BLOG AND ITS OWNER WILL NOT BE HELD LIABLE FOR ANY REACTION THAT MAY HAPPEN TO YOUR PET.


  • Antimicrobials

  • Antibiotics (oral, and sometimes topical) can cause fatal changes in intestinal microflora. (Gram negative bacteria overgrow and cause enterocolitis and diarrhea.) Oral lactobacillus supplements have been used to ameliorate the gastrointestinal side-effects, but their effectiveness is debatable.

    Hamsters:
    Fatal reactions: penicillin, streptomycin, dihydrostreptomycin, erythromycin, lincomycin, clindamycin, and tetracyline
    Antibiotics generally regarded as safe (see dosage table below): trimethoprim-sulfamethoxazole, enrofloxacin, ciprofloxacin, gentamicin, chloramphenicol palmitate, and tetracycline


    Antimicrobials used in Hamsters, Gerbils, Rats and Mice


  • Antiparasitics



  • Ivermectin is safe in most rodents for treatment of endoparasites and ectoparasites
    Dosage: 200 – 400 m g/kg; two treatments, 10 days apart; subcutaneous or oral
    IvomecÒ 1% solution: 1 part IvomecÒ + 19 parts propylene glycol = 1 mg ivermectin/2 ml solution
    For large rodents: ivermectin equine paste (18.7 mg ivermectin/ml), orally or mixed with food
    Pinworms in mice cause perineal pruritus and can be treated with: Ivermectin orally (2 mg/kg, two treatments given 10 days apart); other treatments include mebendazole orally (40 mg/kg two times, 7 days apart), thiabendazole orally (100 mg/kg once a week for 4 weeks), or piperazine citrate mixed with drinking water (200 mg/kg body weight SID for 7 days, wait 7 days, and repeat treatment).
    Lime sulfur diluted 1:40 in water, applied as a dip once a week for 6 weeks
    Sarcoptes mites in guinea pigs, rats, and hamsters
    Fur mites in mice and rats
    *Keep animals in a warm draft-free location after dipping
    1% lindane baths, once a week for 3 weeks
    Sarcoptes mites in guinea pigs
    *Keep animals in a warm draft-free location after dipping
    0.5% malathion dip, sponged on
    Lice in guinea pigs and mice
    NOT SAFE in preweanling animals
    *Keep animals in a warm draft-free location after dipping
    Amitraz: diluted with water according to package directions (wash animals at two-week intervals for 3 - 6 treatments), or diluted at five times the package directions for greater safety (1 bottle per 10 gallons water, and wash animals at two week intervals for 3 - 6 treatments)
    Demodicosis in gerbils, hamsters, and rats
    *Keep animals in a warm draft-free location after dipping
    Flea powders, sprays, and foams approved for cats are usually safe
    Lice, fur mites, fleas in guinea pigs, rats and mice
    Thoroughly clean and sanitize the pet’s environment prior to returning it to that environment. Repeat thorough cleaning with each subsequent treatment.


  • Miscellaneous drugs for various conditions (see table below)
     
  • Dermatophytosis (Trichophyton mentagrophytes) is zoonotic. Treatment must include clearing the lesions and eliminating the organism from the environment (cage and accessories).
    Griseofulvin is teratogenic and should not be used in pregnant animals
    Rats: topical therapy of povidone-iodine (one-time) solution, followed by griseofulvin orally (25 mg/100 g body weight every 10 days for 3 doses
    Guinea pigs: griseofulvin 15 – 75 mg/kg/day for 14 – 28 days (doses up to 100 mg/kg have been reported)
    Topical antifungals applied SID for 2 – 4 weeks may be used for localized or mild disease
    Hypovitaminosis C (scurvy) in guinea pigs can lead to secondary systemic and infectious diseases due to immunosuppression
    All sick guinea pigs should be given supplementation (50 – 100 mg/day, injectable)
    Normal supplementation dose: Vitamin C 200 – 400 mg/liter of drinking water
    Vitamin C deteriorates rapidly in stored feed/water; fresh solutions should be made frequently
    Organophosphate poisoning: treat with atropine
    Anaerobic infection: treat with metronidazole
    Warfarin poisoning: treat with vitamin K
    Delayed parturition: treat with oxytocin



    Miscellaneous drugs used in pet rodents




  • Routes of Administration


  • Drinking water, as a route of administration, has many drawbacks. It is difficult to monitor consumption (especially if in multiple-animal housing), patients tend to drink less (or even none) because of taste and color, and desert dwellers always drink little (healthy or ill).
    Antibiotics, if used in drinking water, must dissolve easily, mix well, and be changed daily. Deionized (not tap) water must be used.
    Oral administration is cheaper and more convenient.
    Parenteral administration is the most effective route, but usually costs more than oral. (Some owners can be taught to give injections at home.)
    Educate clients to monitor closely, discontinue medications at any sign of side effects, and contact the veterinarian if any problems arise. (31)






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